Day 1 Cycle 5 Chemotherapy - 28 July 2025

Day 1 Cycle 5 Chemotherapy - 28 July 2025


SPO2 = 94
BP = 100/77
Pulse = 82
Weight = 66.0 kg

Temp : 36.2 C 

Hb A1c : 5.6

Went back to see Dr Chan this morning.  Whilst the cancer appears to be under control, he is continuing with the chemotherapy, but only with Alimta (permetrexed) maintenance treatment coupled with Tagrisso.  Given my EXON 21 plus TP53, this is the standard that is recommended and had shown a longer PFS and OS under the FLAURA2 trails.

He also reduced the Dexamethasone steroids in the hope of managing the side effect of persistent hiccup, but cautioned that there may be a possibility of rashes on the body with the reduced steroids that is typically a side effect of Alimta.  He also prescribed an antibiotic called Doxycycline 100mg, which has some contraindications with iron, zine and antacids. It also cautioned against excessive skin exposure to sunlight (there goes my morning walks if I have to take this antibiotic. 

With regard to the toe and skin splits, he prescribed a topical gel Dalacin T (Clindamycin Phosphate) to apply to the affected areas.  

I also seem to be getting a bit of a runny nose - probably passed by Patrick who is suffering from a flu.  Better get prepared for that infection and having to deal with it in the coming days.



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